The Biohacker's Mantra
Measure twice, intervene once, verify always. The goal isn't endless tracking—it's finding the few inputs that produce disproportionate outputs for your biology.
¶ Core Tracking & Analytics
Epigenetic clocks (DunedinPACE, GrimAge), telomere length, and measuring biological vs chronological age.
Measuring "inflammaging"—chronic low-grade inflammation. hs-CRP, IL-6, and cytokine profiles.
Comprehensive blood panels for metabolic health, lipids, and hormonal optimization.
Market analysis and evidence-based review of trending supplements and stacking strategies.
¶ The Tracking Stack
| Tier | Target Audience | Key Tests | Approx. Cost |
|---|---|---|---|
| Tier 1 (Essential) | Every 40+ Adult | CMP, Lipids, hs-CRP, HbA1c, Vitamin D | ~$200/yr |
| Tier 2 (Optimizer) | Biohackers | Tier 1 + Hormones, Insulin, Omega-3, Ferritin | ~$800/yr |
| Tier 3 (Frontier) | Early Adopters | Tier 2 + Epigenetic Clock, CGM, Microbiome, VO2 Max | ~$2,000+/yr |
¶ N=1 Experimentation Protocol
- Establish Baseline: Collect 2-4 weeks of data before any intervention. Track subjective markers alongside objective metrics.
- Intervene Precisely: Change ONE variable at a time. Document dose, timing, and brand.
- Measure Outcomes: Retest biomarkers at protocol end (usually 12 weeks). Compare against baseline.
- Decide & Iterate: Continue, modify, or discontinue. Keep a decision log.
⚠️ Critical Warning
Biohacking is not a substitute for medical care. Abnormal results require physician consultation. Self-experimentation with hormones or prescription drugs carries serious risks.
¶ Frequently Asked Questions
How often should I test?
- Essential: Every 6-12 months.
- Optimizing: Every 3-6 months.
- Epigenetic Clocks: Annually (changes are slow).
What's the best biological age test?
DunedinPACE is currently the gold standard for "pace of aging". GrimAge is best for mortality prediction. Avoid cheap, unvalidated consumer tests.
Should I use a CGM if I'm not diabetic?
Yes, for a short period (2-4 weeks). It reveals personalized glucose responses to specific foods and stress that you can't guess.
What wearables do you recommend?
- Sleep: Oura Ring, Whoop.
- HRV: Polar H10 (chest strap) for accuracy, Oura/Apple Watch for trends.