细胞间通讯改变是指细胞间信号传导中与年龄相关的变化，这些变化会破坏组织稳态和器官功能。这一特征涵盖了内分泌、旁分泌、自分泌和近分泌信号通路的功能障碍，导致细胞、组织和器官系统之间的协调受损，最终促成衰老表型和年龄相关疾病。
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属于 衰老标志 系列的一部分