菌群失调（Dysbiosis）是指与年龄相关的微生物组（尤其是肠道微生物组）组成和功能的破坏，它会促进衰老过程和与年龄相关的疾病。这一衰老标志包括微生物多样性的改变、有益菌的减少、致病菌的过度生长，以及受损的微生物组-宿主相互作用，这些相互作用会影响整个生命周期的免疫、代谢和整体健康。
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衰老标志 系列的一部分