The Bottom Line
Lifestyle interventions offer the highest evidence-to-cost ratio of any longevity strategy. Regular exercise, quality sleep, and stress management can extend healthspan by 10+ years with virtually zero risk.
The single most underrated longevity intervention. Glymphatic clearance and DNA repair.
Evidence-based dietary patterns, fasting protocols, and macronutrient optimization.
Muscle as an endocrine organ. Zone 2 cardio, resistance training, and myokines.
Cortisol regulation, HRV training, and modulating the stress response.
Meditation practices to reduce inflammation, improve telomerase activity, and protect cognition.
Social connection as a biological necessity. Reducing mortality risk through relationships.
Vitamin D, nitric oxide, and circadian rhythm entrainment.
Evidence-based remedies for recovering faster from colds and flu.
These 5 interventions capture 80% of the longevity benefit with minimal time investment:
If you could only choose one, sleep offers the highest return on investment. No supplement can compensate for chronic sleep deprivation.
No. Consistency beats intensity. A "good enough" practice done regularly outperforms perfect adherence that isn't sustainable.
For some early-stage conditions, yes, but always consult your physician. Never discontinue prescribed medications without supervision.